bridging the micro-macro gap with diffusion MRI

Clinical Translation

We work on quantifying neurodegeneration (demyelination and axonal loss) and inflammation in the brain; myofiber diameter and membrane permeability in muscle (to detect atrophy); and quantifying glandular lumen size and fraction, as well as size and permeability of stromal cells in the prostate (as promising markers for prostate cancer). 


D. S. Novikov, Fieremans, E., Jensen, J. H., and Helpern, J. A., Random walk with barriers, Nature physics, vol. 7, pp. 508-514, 2011.

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