Biophysics Group

NYU MRI Biophysics Group

Bridging the micro-macro gap with diffusion MRI

WHAT WE DO

Advancing MRI Imaging

We develop novel imaging markers based on advanced yet clinically usable MRI methods and biophysical modeling, as well as their validation and traslation into clinical applications. We are part of the Center of Biomedical Imaging, Department of Radiology at the New York University Grossman School of Medicine.

WHO WE ARE

A multidisciplinary team

Meet All Members

OUR WORK

Latest Publications

Abdollahzadeh A, Coronado-Leija R, Lee HH, Sierra A, Fieremans E and Novikov DS. Scattering approach to diffusion quantifies axonal damage in brain injury. (2025) Nat Commun. 16, 9808 Pubmed Nat Commun PMC Article

Ramos-Cejudo J, Beiser AS, Lu S, Tanner JA, Scott MR, He T, Ghosh S, Johnson KA, Salinas J, Bubu OM, Fieremans E, Convit A, Pomara N, Wisniewski T, Berger JS, Osorio RS, Decarli CS, Johnson AD and Seshadri S. Association of Platelet Aggregation With Markers of Alzheimer Disease Pathology in Middle-Aged Participants of the Framingham Heart Study. (2025) Neurology. 105, e214314 Pubmed Neurology PMC Article

Chung S, Shin SH, Alivar A, McGiffin JN, Coelho S, Rath JF, Fieremans E, Novikov DS, El Berkaoui A, Foo FY, Rashbaum IG, Amorapanth P, Flanagan SR and Lui YW. Linking Symptom Phenotypes to Patterns of White Matter Injury in Mild Traumatic Brain Injury: A Latent Class Analysis. (2025) AJNR Am J Neuroradiol. Pubmed AJNR Am J Neuroradiol

Resources

Our group is committed on contributing developed software to the scientific community by making it freely available on Github, and the open source MRTRIX.

SOFTWARE

ARTIFACT CORRECTION

The correction of the different types of artifacts (Gibbs ringing, EPI distortion, eddy current distortion, motion, etc) as well as noise is necessary for an accurate, precise and robust estimation of diffusion model parameters.

DESIGNER (Diffusion parameter EStImation with Gibbs and NoisE Removal), a postprocessing pipeline for diffusion MRI images
Denoising using Marchenko-Pastur Principal Component Analysis (MP-PCA), available on mrtrix.org (function _dwidenoise_) or as matlab code
Outliers detection, available on visielab.uantwerpen.be/irlls

DIFFUSION PARAMETER ESTIMATION

DTI/DKI processing, available on github.com/NYU-DiffusionMRI/Diffusion-Kurtosis-Imaging (functions DKI_fit.m, DKI_parameters.m)
White Matter Tract Integrity metrics derived from DKI, available on github.com/NYU-DiffusionMRI/Diffusion-Kurtosis-Imaging (function wmti_parameters)
Random Permeable Barrier Model (RPBM): MATLAB code for modeling restriction size and permeability, is available on github.com/NYU-DiffusionMRI/RBPM

AFFILIATIONS

Our Funding Partners

JOIN US

We are now recruiting

We are always looking for talented and passionate scientists who are interested in moving our research forward.

View our detailed job description here.