Biophysics Group

NYU MRI Biophysics Group

Bridging the micro-macro gap with diffusion MRI

WHAT WE DO

Advancing MRI Imaging

We develop novel imaging markers based on advanced yet clinically usable MRI methods and biophysical modeling, as well as their validation and traslation into clinical applications. We are part of the Center of Biomedical Imaging, Department of Radiology at the New York University Grossman School of Medicine.

WHO WE ARE

A multidisciplinary team

Meet All Members

OUR WORK

Latest Publications

Voronova AK, Grigoriou A, Bernatowicz K, Simonetti S, Serna G, Roson N, Escobar M, Vieito M, Nuciforo P, Toledo R, Garralda E, Fieremans E, Novikov DS, Palombo M, Perez-Lopez R and Grussu F. SpinFlowSim: A blood flow simulation framework for histology-informed diffusion MRI microvasculature mapping in cancer. (2025) Med Image Anal. 102, 103531 Pubmed Med Image Anal

Tian Q, Ngamsombat C, Lee HH, Berger DR, Wu Y, Fan Q, Bilgic B, Li Z, Novikov DS, Fieremans E, Rosen BR, Lichtman JW and Huang SY. Quantifying axonal features of human superficial white matter from three-dimensional multibeam serial electron microscopy data assisted by deep learning. (2025) Neuroimage. 121212 Pubmed Neuroimage

Fokas E, Taga M, Hayes L, Charalambous CC, Raju S, Wang Z, Shao Y, Mazzoni P, Stepanov V, Fieremans E and Schambra H. Transcallosal inhibition does not influence subacute motor recovery in mild-to-moderate stroke. (2025) Brain. Pubmed Brain

Resources

Our group is committed on contributing developed software to the scientific community by making it freely available on Github, and the open source MRTRIX.

SOFTWARE

ARTIFACT CORRECTION

The correction of the different types of artifacts (Gibbs ringing, EPI distortion, eddy current distortion, motion, etc) as well as noise is necessary for an accurate, precise and robust estimation of diffusion model parameters.

DESIGNER (Diffusion parameter EStImation with Gibbs and NoisE Removal), a postprocessing pipeline for diffusion MRI images
Denoising using Marchenko-Pastur Principal Component Analysis (MP-PCA), available on mrtrix.org (function _dwidenoise_) or as matlab code
Outliers detection, available on visielab.uantwerpen.be/irlls

DIFFUSION PARAMETER ESTIMATION

DTI/DKI processing, available on github.com/NYU-DiffusionMRI/Diffusion-Kurtosis-Imaging (functions DKI_fit.m, DKI_parameters.m)
White Matter Tract Integrity metrics derived from DKI, available on github.com/NYU-DiffusionMRI/Diffusion-Kurtosis-Imaging (function wmti_parameters)
Random Permeable Barrier Model (RPBM): MATLAB code for modeling restriction size and permeability, is available on github.com/NYU-DiffusionMRI/RBPM

AFFILIATIONS

Our Funding Partners

JOIN US

We are now recruiting

We are always looking for talented and passionate scientists who are interested in moving our research forward.

View our detailed job description here.